PD-1 抗体 (AA 21-167)
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Quick Overview for PD-1 抗体 (AA 21-167) (ABIN263912)
抗原
See all PD-1 (PDCD1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 21-167
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特异性
- This antibody detects PDCD1.
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产品特性
- Synonyms: Protein PD-1, hPD-1, PDCD1, Programmed cell death protein 1
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纯化方法
- Protein-G affinity chromatography
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免疫原
- Recombinant human PDCD1 (21-167aa) purified from E. coli
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亚型
- IgG2b
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应用备注
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ELISA. Western blot: 1: 500 (starting dilution) approx. 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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别名
- CD279 / PD1
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背景
- PDCD1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PDCD1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney. PDCD1 might be involved in the regulation of peripheral tolerance and may help prevent autoimmune diseases.Synonyms: PDCD1, Programmed cell death protein 1, Protein PD-1, hPD-1
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基因ID
- 5133
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UniProt
- Q15116
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途径
- Cancer Immune Checkpoints
抗原
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