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PD-1 抗体 (AA 21-167)

This anti-PD-1 antibody is a 小鼠 单克隆 antibody detecting PD-1 in WB 和 EIA. Suitable for 人.
产品编号 ABIN263912
发货至: 中国

Quick Overview for PD-1 抗体 (AA 21-167) (ABIN263912)

抗原

See all PD-1 (PDCD1) 抗体
PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PD-1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

4F12
  • 抗原表位

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    AA 21-167

    特异性

    This antibody detects PDCD1.

    产品特性

    Synonyms: Protein PD-1, hPD-1, PDCD1, Programmed cell death protein 1

    纯化方法

    Protein-G affinity chromatography

    免疫原

    Recombinant human PDCD1 (21-167aa) purified from E. coli

    亚型

    IgG2b
  • 应用备注

    ELISA. Western blot: 1: 500 (starting dilution) approx. 1: 1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Phosphate-Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

    别名

    CD279 / PD1

    背景

    PDCD1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PDCD1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney. PDCD1 might be involved in the regulation of peripheral tolerance and may help prevent autoimmune diseases.Synonyms: PDCD1, Programmed cell death protein 1, Protein PD-1, hPD-1

    基因ID

    5133

    UniProt

    Q15116

    途径

    Cancer Immune Checkpoints
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