APOA1 抗体
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北京 101111
Quick Overview for APOA1 抗体 (ABIN263693)
抗原
See all APOA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes Apolipoprotein A I. This antibody does not cross react with Apo AII or Apo B in competitive RIA.Aff. Const.:5 x 10e6 L/m (determined by RIA followed by Scatchard plot analysis)
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产品特性
- Synonyms: APOA1, ApoA-I, Apo-AI, ApoAI
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纯化方法
- Protein A chromatography
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纯度
- > 90 % pure (SDS-PAGE)
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免疫原
- Human high density lipoprotein
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亚型
- IgG2a
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anti-Apolipoprotein A-I (APOA1) antibody
APOA1 适用: 小鼠 WB, IHC, ELISA, IP 宿主: 山羊 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 122-267) antibodyAPOA1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C13 unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 25-264) antibodyAPOA1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 25-265) antibodyAPOA1 适用: 兔 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 1-267) antibodyAPOA1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal S1 unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 1-267) antibodyAPOA1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 10-37) antibodyAPOA1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 51-150) antibodyAPOA1 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), FACS, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) antibodyAPOA1 适用: 小鼠, 大鼠 WB, IHC, ELISA, IHC (p), ID 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (N-Term) antibodyAPOA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 5.3 mg/mL (OD280nm, E0.1% = 1.4)
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缓冲液
- 10 mM Phosphate, pH 7.4 containing 150 mM Sodium chloride and 0,09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one week or (in aliquots) at -40 °C for longer. If aliquoted for long term storage, fill volume should be equal to or greater than 50% of thenominal fill volume of the vial used. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- APOA1 (Apolipoprotein A-I (APOA1))
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别名
- Apolipoprotein A I (APO AI)
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背景
- Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids, an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.Synonyms: APOA1, Apo-AI, ApoA-I, ApoAI
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基因ID
- 335
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UniProt
- P02647
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途径
- Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
抗原
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