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SIRT2 抗体 (AA 165-187)

This anti-SIRT2 antibody is a 兔 多克隆 antibody detecting SIRT2 in WB, IHC 和 IHC (p). Suitable for 人, 大鼠, 小鼠, 猴, Chimpanzee 和 Orang-Utan.
产品编号 ABIN2628313
发货至: 中国

Quick Overview for SIRT2 抗体 (AA 165-187) (ABIN2628313)

抗原

See all SIRT2 抗体
SIRT2 (Sirtuin 2 (SIRT2))

适用

  • 75
  • 57
  • 50
  • 7
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠, 猴, Chimpanzee, Orang-Utan

宿主

  • 75
  • 11
  • 1

克隆类型

  • 65
  • 22
多克隆

标记

  • 50
  • 9
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIRT2 antibody is un-conjugated

应用范围

  • 56
  • 18
  • 17
  • 16
  • 14
  • 12
  • 11
  • 10
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 165-187

    特异性

    Isoform 1 is expressed in heart, liver and skeletal muscle, weakly expressed in the cortex. Isoform 2 is strongly expressed in the cortex, weakly expressed in heart and liver. Weakly expressed in several malignancies including breast, liver, brain, kidney and prostate cancers compared to normal tissues. Weakly expressed in glioma cell lines compared to normal brain tissues (at protein level). Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network. .

    纯化方法

    Immunogen affinity purified

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human SIRT2(165-187aa YTQNIDTLERIAGLEQEDLVEAH), different from the related mouse and rat sequences by three amino acids.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    Distilled water

    浓度

    Lot specific

    缓冲液

    Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
  • 抗原

    SIRT2 (Sirtuin 2 (SIRT2))

    别名

    SIRT2 / Sirtuin 2

    背景

    Name/Gene ID: SIRT2

    Synonyms: SIRT2, SIR2, Sir2-related protein type 2, SIR2L, SIR2L2, Sirtuin 2, Silent information regulator 2, SIR2-like protein 2, Sirtuin type 2

    基因ID

    22933
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