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tau 抗体 (pSer202, pSer519)

The 兔 多克隆 anti-tau antibody (ABIN2568469) specifically detects tau in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN2568469
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for tau 抗体 (pSer202, pSer519) (ABIN2568469)

抗原

See all tau 抗体
tau (tau Protein)

适用

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人, 小鼠, 大鼠

宿主

  • 742
  • 41
  • 4
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克隆类型

  • 631
  • 156
  • 2
多克隆

标记

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This tau antibody is un-conjugated

应用范围

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  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

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    pSer202, pSer519

    特异性

    The antibody detects endogenous levels of Tau only when phosphorylated at serine 519/202.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    免疫原

    Tau (phospho Ser519/202) antibody was raised against a peptide sequence around phosphorylation site of Serine 519/202 (P-G-S (p)-P-G) derived from Human Tau.

    亚型

    IgG
  • 应用备注

    Western Blot: 1:500~1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    tau (tau Protein)

    别名

    tau

    背景

    Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

    分子量

    85 kDa

    基因ID

    4137

    NCBI登录号

    NP_058519

    UniProt

    P10636
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