CD70 抗体
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北京 101111
Quick Overview for CD70 抗体 (ABIN2567915)
抗原
See all CD70 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The FR70 monoclonal antibody specifically binds to mouse CD70, a 30-33 kDA type II transmembrane protein and member of the TNF superfamily.
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纯化方法
- The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
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亚型
- IgG2b kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-buffered aqueous solution, ph7.2.
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储存条件
- 4 °C
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储存方法
- The product should be stored undiluted at 4°C. Do not freeze.
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- CD70 (CD70 Molecule (CD70))
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别名
- CD70
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背景
- The FR70 monoclonal antibody specifically binds to mouse CD70, a 30-33 kDA type II transmembrane protein and member of the TNF superfamily. CD70 is the ligand for CD27 and is expressed on dendritic cells, activated B cell, and a subset of activated T cells at lower levels. Its main role is in regulating B cell activation and immunoglobulin synthesis. CD70 expressing cells are able to co-stimulate T cell proliferation and upregulate cytokine production. The FR70 antibody is reported to block the binding of CD70 to CD27.
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基因ID
- 21948
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UniProt
- O55237
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途径
- Cancer Immune Checkpoints
抗原
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