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CD4 抗体

This anti-CD4 antibody is a 大鼠 单克隆 antibody detecting CD4 in FACS, IHC, IP 和 Func. Suitable for 小鼠.
产品编号 ABIN2567633
发货至: 中国

Quick Overview for CD4 抗体 (ABIN2567633)

抗原

See all CD4 抗体
CD4

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD4 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Functional Studies (Func)

克隆位点

GK1-5
  • 特异性

    The GK1.5 monoclonal antibody specifically binds with the mouse CD4 Molecule, also known as L3T4, a 55 kDa differentiation antigen which binds to the MHC class II.

    纯化方法

    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2 mg/mL

    缓冲液

    Phosphate-buffered aqueous solution, ph7.2.

    储存条件

    4 °C

    储存方法

    The product should be stored undiluted at 4°C. Do not freeze.
  • 抗原

    CD4

    别名

    CD4

    背景

    The GK1.5 monoclonal antibody specifically binds with the mouse CD4 Molecule, also known as L3T4, a 55 kDa differentiation antigen which binds to the MHC class II. CD4 is expressed on most thymocytes, a subpopulation of mature T lymphocytes, dendritic cells, pluripotent hematopoietic stem cells, B cell precursors, and lymphoid precursors inside the thymus. It is also expressed on the mouse egg cell membrane, enhancing adhesion to MHC class II bearing sperm. By interaction with MHC class II on the surface of APC, CD4 initiates the development of T lymphocytes and helps the optimum functioning of mature T lymphocytes. The binding of the GK1.5 antibody blocks the binding of the Anti-Mouse CD4 RM4-5 antibody.

    基因ID

    12504

    UniProt

    P06332

    途径

    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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