TLR4 抗体 (PE)
Quick Overview for TLR4 抗体 (PE) (ABIN2567456)
抗原
See all TLR4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The UT41 monoclonal antibody specifically reacts with mouse CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4).
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纯化方法
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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储存条件
- 4 °C
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储存方法
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- TLR4 (Toll-Like Receptor 4 (TLR4))
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别名
- CD284
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背景
- The UT41 monoclonal antibody specifically reacts with mouse CD284, a 110kDA type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4). The complex of TLR-4, MD-2, and CD14 regulates the innate immune system recognition of bacterial lipopolysaccharides (LPS) and is expressed on the surface of thioglycollate-elicited macrophages. The UT41 antibody can bind to TLR4 with or without the formation of the TLR4/MD-2 complex.
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基因ID
- 21898
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UniProt
- Q9QUK6
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
抗原
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