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CD28 抗体

The 仓鼠 单克隆 anti-CD28 antibody (Clone 37-51) (ABIN2567437) specifically detects CD28 in FACS, IP 和 Func. The antibody is reactive with 小鼠 samples.
产品编号 ABIN2567437
发货至: 中国
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Quick Overview for CD28 抗体 (ABIN2567437)

抗原

See all CD28 抗体
CD28

适用

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小鼠

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仓鼠

克隆类型

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单克隆

标记

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This CD28 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

克隆位点

37-51
  • 特异性

    The 37.51 monoclonal antibody specifically reacts with mouse CD28 Molecule, a 45 kDa homodimer.

    纯化方法

    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2 mg/mL

    缓冲液

    Phosphate-buffered aqueous solution, ph7.2.

    储存条件

    4 °C

    储存方法

    The product should be stored undiluted at 4°C. Do not freeze.
  • 抗原

    CD28

    别名

    CD28

    背景

    The 37.51 monoclonal antibody specifically reacts with mouse CD28 Molecule, a 45 kDa homodimer. It is expressed on most thymocytes, at low density on most of the CD4+ and CD8+ peripheral T lymphocytes, and on the natural killer cells. It is additionally found on activated splenocytes, mast cells, and thymocytes. CD 28 is a costimulator of T lymphocytes and a ligand for CD80 (B7-1), and CD86 (B7-2). The CD28 signaling stimulates the expression of IL-2 and IL-2 receptor and the cytotoxicity of CD3-activated T lymphocytes.The 37.51 antibody stimulates the proliferation of T lymphocytes and natural killer cells and their respective cytokine production.

    基因ID

    12487

    UniProt

    P31041

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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