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CD28 抗体

CD28 适用: 小鼠 FACS, IP, Func 宿主: 仓鼠 Monoclonal 37-51 unconjugated
产品编号 ABIN2567436
发货至: 中国
  • 抗原 See all CD28 抗体
    CD28
    适用
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    小鼠
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    仓鼠
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    标记
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    This CD28 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
    特异性
    The 37.51 monoclonal antibody specifically reacts with mouse CD28 Molecule, a 45 kDa homodimer.
    纯化方法
    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
    克隆位点
    37-51
    亚型
    IgG
    Top Product
    Discover our top product CD28 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2 mg/mL
    缓冲液
    Phosphate-buffered aqueous solution, ph7.2.
    储存条件
    4 °C
    储存方法
    The product should be stored undiluted at 4°C. Do not freeze.
  • 抗原
    CD28
    别名
    CD28 (CD28 产品)
    背景
    The 37.51 monoclonal antibody specifically reacts with mouse CD28 Molecule, a 45 kDa homodimer. It is expressed on most thymocytes, at low density on most of the CD4+ and CD8+ peripheral T lymphocytes, and on the natural killer cells. It is additionally found on activated splenocytes, mast cells, and thymocytes. CD 28 is a costimulator of T lymphocytes and a ligand for CD80 (B7-1), and CD86 (B7-2). The CD28 signaling stimulates the expression of IL-2 and IL-2 receptor and the cytotoxicity of CD3-activated T lymphocytes.The 37.51 antibody stimulates the proliferation of T lymphocytes and natural killer cells and their respective cytokine production.
    基因ID
    12487
    UniProt
    P31041
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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