CD28 抗体 (APC)
-
- 抗原 See all CD28 抗体
- CD28
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This CD28 antibody is conjugated to APC
-
应用范围
- Flow Cytometry (FACS)
- 特异性
- The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes.
- 纯化方法
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- 克隆位点
- CD28-2
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CD28 Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- 储存条件
- 4 °C
- 储存方法
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
-
- 抗原
- CD28
- 别名
- CD28 (CD28 产品)
- 背景
- The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86), a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 Molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction.
- 基因ID
- 920
- UniProt
- P10747
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
-