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PD-L1 抗体

This anti-PD-L1 antibody is a 大鼠 单克隆 antibody detecting PD-L1 in FACS 和 Func. Suitable for 小鼠.
产品编号 ABIN2567408
发货至: 中国

Quick Overview for PD-L1 抗体 (ABIN2567408)

抗原

See all PD-L1 抗体
PD-L1 (CD274 (PD-L1))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This PD-L1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Functional Studies (Func)

克隆位点

10F-9G2
  • 特异性

    The 10F.9G2 monoclonal antibody specifically reacts with mouse CD274, also known as B7-H1 or PD-L1, a 43 kDa glycoprotein of the B7 family of the immunoglobulin superfamily.

    纯化方法

    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2 mg/mL

    缓冲液

    Phosphate-buffered aqueous solution, ph7.2.

    储存条件

    4 °C

    储存方法

    The product should be stored undiluted at 4°C. Do not freeze.
  • 抗原

    PD-L1 (CD274 (PD-L1))

    别名

    CD274

    背景

    The 10F.9G2 monoclonal antibody specifically reacts with mouse CD274, also known as B7-H1 or PD-L1, a 43 kDa glycoprotein of the B7 family of the immunoglobulin superfamily. CD274 is expressed on the B and T lymphocytes, natural killer cells, and dendritic cells. The receptor for the B7-H1 Molecule is PD-1, which contains an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM), and is expressed on activated B and T cells. The interaction between CD274 and PD-1 seems to downregulate the T and B immune responses.

    基因ID

    29126

    UniProt

    Q9NZQ7

    途径

    Cancer Immune Checkpoints
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