IL7R 抗体 (PE-Cy5)
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北京 101111
Quick Overview for IL7R 抗体 (PE-Cy5) (ABIN2567211)
抗原
See all IL7R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The RDR5 monoclonal antibody specifically reacts with human CD127, a 60-90 kDA type I transmembrane glycoprotein also known as the IL-7 receptor alpha chain.
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纯化方法
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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储存条件
- 4 °C
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储存方法
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- IL7R (Interleukin 7 Receptor (IL7R))
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别名
- CD127
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背景
- The RDR5 monoclonal antibody specifically reacts with human CD127, a 60-90 kDA type I transmembrane glycoprotein also known as the IL-7 receptor alpha chain. CD127 binds with CD132 (gamma c) to forms the IL-7 receptor that is expressed on mature T cells and immature B cells. Since CD127 expression is downregulated in Treg cells, it can be used as a marker for differentiating them from common T cells. The binding of the RDR5 antibody can be blocked by pre-incubating the cells with human IL-7.
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基因ID
- 3575
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UniProt
- P16871
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
抗原
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