The ICRF44 monoclonal antibody specifically reacts with the 165 kDa human adhesion glycoprotein CD11b, which forms, together with the 95 kDa CD18 (integrin β2) a complex known as Mac-1.
纯化方法
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
抗原
CD11b (ITGAM)
(Integrin alpha M (ITGAM))
别名
CD11b
背景
The ICRF44 monoclonal antibody specifically reacts with the 165 kDa human adhesion glycoprotein CD11b, which forms, together with the 95 kDa CD18 (integrin β2) a complex known as Mac-1. CD11b is expressed on the surface of activated lymphocytes, a subset of natural killer cells, granulocytes, and monocytes. It functions as a receptor in cell-cell and cell-matrix interactions and as a receptor for iC3b, ICAM-1, ICAM-2, and ICAM-3 intercellular adhesion molecules.