KIT 抗体 (PE)
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北京 101111
Quick Overview for KIT 抗体 (PE) (ABIN2567120)
抗原
See all KIT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The YB5.B8 monoclonal antibody specifically binds with human CD117 (c-kit), the 145 kDA receptor for stem cell factor (SCF) or steel factor.
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纯化方法
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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储存条件
- 4 °C
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储存方法
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
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别名
- CD117
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背景
- The YB5.B8 monoclonal antibody specifically binds with human CD117 (c-kit), the 145 kDA receptor for stem cell factor (SCF) or steel factor. This tyrosine kinase protein is expressed mainly on hematopoietic progenitor, mast cells, acute myeloid leukemia cells (AML). CD117 activation promotes proliferation and cell differentiation on these cell subtypes. A lack or defect of SCF can lead to a decrease in number of hematopoietic progenitor cells and severe anemia.
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基因ID
- 3815
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UniProt
- P10721
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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