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KIT 抗体 (PE)

KIT 适用: 人 FACS 宿主: 小鼠 Monoclonal YB5-B8 PE
产品编号 ABIN2567119
发货至: 中国
  • 抗原 See all KIT 抗体
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This KIT antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    The YB5.B8 monoclonal antibody specifically binds with human CD117 (c-kit), the 145 kDA receptor for stem cell factor (SCF) or steel factor.
    纯化方法
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    克隆位点
    YB5-B8
    亚型
    IgG1 kappa
    Top Product
    Discover our top product KIT Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    储存条件
    4 °C
    储存方法
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • 抗原
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    别名
    CD117 (KIT 产品)
    背景
    The YB5.B8 monoclonal antibody specifically binds with human CD117 (c-kit), the 145 kDA receptor for stem cell factor (SCF) or steel factor. This tyrosine kinase protein is expressed mainly on hematopoietic progenitor, mast cells, acute myeloid leukemia cells (AML). CD117 activation promotes proliferation and cell differentiation on these cell subtypes. A lack or defect of SCF can lead to a decrease in number of hematopoietic progenitor cells and severe anemia.
    基因ID
    3815
    UniProt
    P10721
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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