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KIT 抗体 (PE)
KIT
适用: 人
FACS
宿主: 小鼠
Monoclonal
YB5-B8
PE
KIT抗体详情 (PE)
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抗原
See all KIT 抗体
KIT
(Mast/stem Cell Growth Factor Receptor (KIT))
适用
All reactivities for KIT 抗体
人
宿主
All hosts for KIT 抗体
小鼠
克隆类型
All clonalities for KIT 抗体
单克隆
标记
All conjugates for KIT 抗体
This KIT antibody is conjugated to PE
应用范围
All applications for KIT 抗体
Flow Cytometry (FACS)
特异性
The YB5.B8 monoclonal antibody specifically binds with human CD117 (c-kit), the 145 kDA receptor for stem cell factor (SCF) or steel factor.
纯化方法
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
克隆位点
YB5-B8
亚型
IgG1 kappa
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
储存条件
4 °C
储存方法
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
KIT目标详情
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抗原
KIT
(Mast/stem Cell Growth Factor Receptor (KIT))
别名
CD117 (KIT 产品 )
背景
The YB5.B8 monoclonal antibody specifically binds with human CD117 (c-kit), the 145 kDA receptor for stem cell factor (SCF) or steel factor. This tyrosine kinase protein is expressed mainly on hematopoietic progenitor, mast cells, acute myeloid leukemia cells (AML). CD117 activation promotes proliferation and cell differentiation on these cell subtypes. A lack or defect of SCF can lead to a decrease in number of hematopoietic progenitor cells and severe anemia.
基因ID
3815
UniProt
P10721
途径
RTK signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Sensory Perception of Sound , Stem Cell Maintenance , Production of Molecular Mediator of Immune Response , Regulation of long-term Neuronal Synaptic Plasticity
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