The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
抗原
KIT
(Mast/stem Cell Growth Factor Receptor (KIT))
别名
CD117
背景
The YB5.B8 monoclonal antibody specifically binds with human CD117 (c-kit), the 145 kDA receptor for stem cell factor (SCF) or steel factor. This tyrosine kinase protein is expressed mainly on hematopoietic progenitor, mast cells, acute myeloid leukemia cells (AML). CD117 activation promotes proliferation and cell differentiation on these cell subtypes. A lack or defect of SCF can lead to a decrease in number of hematopoietic progenitor cells and severe anemia.