KIT 抗体 (APC)
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北京 101111
Quick Overview for KIT 抗体 (APC) (ABIN2567118)
抗原
See all KIT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene.
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纯化方法
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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亚型
- IgG2b kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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储存条件
- 4 °C
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储存方法
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
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别名
- CD117
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背景
- The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene. The c-Kit receptor, also known as stem cell factor receptor, is expressed on hematopoietic progenitor cells in adult bone marrow, in progenitors of erythroid and myeloid lineages, and precursors of B and T cells. CD117 enhances the proliferation and the differentiation of the hematopoietic progenitor cells and seems to enhance the development of T cells, as the c-Kit receptor and its ligand are expressed by the thymus.
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基因ID
- 16590
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UniProt
- P05532
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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