CRBN 抗体 (PE)
Quick Overview for CRBN 抗体 (PE) (ABIN2559686)
抗原
See all CRBN 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CRBN
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亚型
- IgG
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anti-Cereblon (CRBN) (AA 1-280) antibody
CRBN 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cereblon (CRBN) (AA 1-442) antibodyCRBN 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cereblon (CRBN) (AA 35-84) antibodyCRBN 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Hamster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- FCM(1:20-100)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at 4°C
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有效期
- 12 months
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- CRBN (Cereblon (CRBN))
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别名
- CRBN
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背景
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CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue. CRBN functions are thought to be related to energy metabolism, learning and memory. Localized to the cytoplasm, CRBN acts as a protease in mitochondria and is thought to regulate the assembly of KCNT1, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, such as the hippocampus. The gene encoding CRBN belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis. Defects in the CRBN gene are associated with mild mental retardation.
Synonyms: Cereblon, DKFZp781K0715, MGC27358, MRT2A, OTTHUMP00000209555, piL, Protein cereblon, Protein x 0001, 2610203G15Rik, 2900045O07Rik, AF229032, AW108261, CRBN_HUMAN.
抗原
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