Abeta 1-42 抗体
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北京 101111
Quick Overview for Abeta 1-42 抗体 (ABIN249343)
抗原
See all Abeta 1-42 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-Abeta (1-42) | Amyloid-beta peptide 1-42
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交叉反应 (详细)
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Human
Not reactive in: No confirmed exceptions from predicted reactivity are currently known -
预测反应
- Bovine,Chicken,Dog,Porcine,Rabbit
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纯化方法
- Serum
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免疫原
- Synthetic peptide chosen from human Abeta (1-42) protein. Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A
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应用备注
- 1 : 1000 (DB), 1 : 3000 (ELISA), 1-2 μL/mL (IL)
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说明
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the antibody can detect Abeta (1-42), Abeta (1-28) Abeta (1-20) and Abeta (1-17). This product exhibits a low reactivity to monomeric Abeta (1-42) as determined by SDS-PAGE and Western blotting.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For reconstitution add 100 μL of sterile water
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缓冲液
- Serum
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注意事项
- Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube
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储存条件
- -20 °C
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储存方法
- Store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
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: "Amyloid-? oligomer specificity mediated by the IgM isotype--implications for a specific protective mechanism exerted by endogenous auto-antibodies." in: PLoS ONE, Vol. 5, Issue 11, pp. e13928, (2010) (PubMed).
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: "Amyloid-? oligomer specificity mediated by the IgM isotype--implications for a specific protective mechanism exerted by endogenous auto-antibodies." in: PLoS ONE, Vol. 5, Issue 11, pp. e13928, (2010) (PubMed).
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- Abeta 1-42 (Amyloid beta 1-42 (Abeta 1-42))
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别名
- Amyloid-beta 42 protein (Abeta (1-42))
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背景
- Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P05067
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分子量
- 4.5 kDa
抗原
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