SCN3B 抗体 (AA 1-215) (Atto 594)
Quick Overview for SCN3B 抗体 (AA 1-215) (Atto 594) (ABIN2485579)
抗原
See all SCN3B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-215
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特异性
- Detects ~40 kDa. Does not cross-reat with NavBeta1, Navbeta2, or Navbeta4.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Fusion protein amino acids 1-215 (full-length) of rat NavBeta3
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亚型
- IgG2b
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anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (AA 1-215) antibody
SCN3B 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S396-29 unconjugated
anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (AA 1-215) antibody (HRP)SCN3B 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S396-29 HRP
anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (AA 1-215) antibody (FITC)SCN3B 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S396-29 FITC
anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (AA 1-215) antibody (Biotin)SCN3B 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S396-29 Biotin
anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (AA 1-215) antibody (PE)SCN3B 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S396-29 PE
anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (AA 1-215) antibody (APC)SCN3B 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S396-29 APC
anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (AA 1-215) antibody (PerCP)SCN3B 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S396-29 PerCP
anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (AA 1-215) antibody (Atto 488)SCN3B 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S396-29 Atto 488
anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (AA 1-215) antibody (Atto 390)SCN3B 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S396-29 Atto 390
anti-Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B) (AA 65-114) antibodySCN3B 适用: 大鼠, 人, 小鼠, Cow, 马, 兔, 猴 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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说明
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A 1:100 dilution of ABIN2485579 was sufficient for detection of NavBeta3 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- SCN3B (Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B))
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别名
- NaVbeta3
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背景
- Nav Beta 3 (SCN3B) belongs to the voltage-gated sodium channel group, and modulates channel gating kinetics. It inactivates the sodium channel opening more slowly than its Beta1 subunit. It is also unique in causing persistent sodium currents which are thought to amplify summation of synaptic imputs which is likely to increase the excitability of specific neurons to their individual inputs (2). Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons (1, 2). Defects in SCN3B are the cause of Brugada syndrome (3).
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基因ID
- 245956
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NCBI登录号
- NP_620797
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UniProt
- Q9JK00
抗原
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