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MDC1 抗体 (N-Term) (APC)

This anti-MDC1 antibody is a 小鼠 单克隆 antibody detecting MDC1 in WB, IF 和 ICC. Suitable for 小鼠.
产品编号 ABIN2484150
发货至: 中国

Quick Overview for MDC1 抗体 (N-Term) (APC) (ABIN2484150)

抗原

See all MDC1 抗体
MDC1 (Mdc1 (MDC1))

适用

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小鼠

宿主

  • 50
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小鼠

克隆类型

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单克隆

标记

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This MDC1 antibody is conjugated to APC

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

P2B11
  • 抗原表位

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    N-Term

    特异性

    Detects ~184 kDa. This antibody recognizes MDC1 at and around the N-terminus.

    交叉反应

    Chimpanzee, Cow, 人, 小鼠

    纯化方法

    Protein G Purified

    免疫原

    GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus

    亚型

    IgG1
  • 应用备注

    • WB (1:2000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.

    说明

    0.5 μg/ml of ABIN2484150 was sufficient for detection of MDC1 in 10 μg of HeLa cell lysate by ECL immunoblot analysis.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Conjugated antibodies should be stored at 4°C
  • 抗原

    MDC1 (Mdc1 (MDC1))

    别名

    MDC1

    背景

    MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.

    基因ID

    240087

    NCBI登录号

    NP_001010833

    UniProt

    Q5PSV9
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