MDC1 抗体 (N-Term) (Atto 390)
Quick Overview for MDC1 抗体 (N-Term) (Atto 390) (ABIN2484141)
抗原
See all MDC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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特异性
- Detects ~184 kDa. This antibody recognizes MDC1 at and around the N-terminus.
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交叉反应
- Chimpanzee, Cow, 人, 小鼠
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纯化方法
- Protein G Purified
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免疫原
- GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus
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亚型
- IgG1
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应用备注
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- WB (1:2000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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说明
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0.5 μg/ml of ABIN2484141 was sufficient for detection of MDC1 in 10 μg of HeLa cell lysate by ECL immunoblot analysis.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- MDC1 (Mdc1 (MDC1))
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别名
- MDC1
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背景
- MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.
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基因ID
- 240087
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NCBI登录号
- NP_001010833
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UniProt
- Q5PSV9
抗原
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