AMIGO1 抗体 (AA 554-574) (APC)
Quick Overview for AMIGO1 抗体 (AA 554-574) (APC) (ABIN2483810)
抗原
See all AMIGO1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 554-574
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特异性
- Detects ~60-80 kDa depending on maturity/glycosylation.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Fusion protein amino acids 554-574 (cytoplasmic C-terminus) of human AMIGO-1
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亚型
- IgG1
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应用备注
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml of ABIN2483810 was sufficient for detection of AMIGO-1 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- AMIGO1 (Adhesion Molecule with Ig-Like Domain 1 (AMIGO1))
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别名
- AMIGO1
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背景
- The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO1, AMIGO2 and AMIGO3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. They can form complexes with each other, but can also self-bind. AMIGO1, also designated Alivin2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO2 (Alivin1) is crucial for depolarization-dependent survival. Similar to AMIGO1 and AMIGO2, AMIGO3 (Alivin3) plays a role in hemophilic and/or heterophilic cell-cell interaction and signal transduction.
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基因ID
- 57463
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NCBI登录号
- NP_065754
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UniProt
- Q86WK6
抗原
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