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CD28 抗体

Cited in 3+ publications. The 小鼠 单克隆 anti-CD28 antibody (Clone E18) (ABIN2479686) specifically detects CD28 in FACS 和 Func. The antibody is reactive with 小鼠 samples.
产品编号 ABIN2479686
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD28 抗体 (ABIN2479686)

抗原

See all CD28 抗体
CD28

适用

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小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD28 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Functional Studies (Func)

克隆位点

E18
  • 产品特性

    Purified IgG

    内毒素水平

    Low endotoxin

    免疫原

    Alternate immunisation with A20 cells expressing mCD28 and recombinant mCD28Ig.

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL
  • Gogishvili, Lühder, Kirstein, Nieuwenhuizen, Goebbels, Beer-Hammer, Pfeffer, Reuter, Taube, Brombacher, Hünig: "Interruption of CD28-mediated costimulation during allergen challenge protects mice from allergic airway disease." in: The Journal of allergy and clinical immunology, Vol. 130, Issue 6, pp. 1394-403.e4, (2012) (PubMed).

    Beyersdorf, Ding, Blank, Dennehy, Kerkau, Hünig: "Protection from graft-versus-host disease with a novel B7 binding site-specific mouse anti-mouse CD28 monoclonal antibody." in: Blood, Vol. 112, Issue 10, pp. 4328-36, (2008) (PubMed).

    Dennehy, Elias, Zeder-Lutz, Ding, Altschuh, Lühder, Hünig: "Cutting edge: monovalency of CD28 maintains the antigen dependence of T cell costimulatory responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 10, pp. 5725-9, (2006) (PubMed).

  • 抗原

    CD28

    别名

    CD28

    基因ID

    12487

    UniProt

    P31041

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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