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c-MYC 抗体 (C-Term)

This anti-c-MYC antibody is a 小鼠 单克隆 antibody detecting c-MYC in WB, ELISA, FACS, IHC (p) 和 IHC (fro). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2477752
发货至: 中国

Quick Overview for c-MYC 抗体 (C-Term) (ABIN2477752)

抗原

See all c-MYC (MYC) 抗体
c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This c-MYC antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

9E10
  • 抗原表位

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    AA 408-439, C-Term

    原理

    MOUSE ANTI C-MYC

    产品特性

    Mouse anti c-myc antibody, clone 9E10 detects the p62c-myc proto-oncogene protein, which is involved in the regulation of the cell cycle and cell growth. C-myc is primarily located to the cell nucleus, but has also been shown to localized to the cytoplasm in several cell lines (Craig et al. 1993). Overexpression of c-myc has been reported in a wide variety of human cancers (Nesbit et al. 1999).Mouse anti c-myc antibody, clone 9E10 recognizes the sequence EQKLISEEDL and may be used to detect proteins and peptides labelled with molecular tags containing this sequence (Hilpert et al. 2001).

    纯化方法

    Purified IgG prepared by affinity chromatography on Protein G

    免疫原

    Synthetic peptide sequence corresponding to the C-terminal region (residues 408-439) of human c-myc conjugated to keyhole limpet hemocyanin.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline,0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    RT,4 °C,-20 °C

    储存方法

    This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
  • Borodina, Jensen, Søndergaard, Poulsen: "Display of wasp venom allergens on the cell surface of Saccharomyces cerevisiae." in: Microbial cell factories, Vol. 9, pp. 74, (2010) (PubMed).

  • 抗原

    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

    别名

    C-MYC

    基因ID

    4609

    UniProt

    P01106

    途径

    p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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