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Transferrin 抗体 (N-Term)

This anti-Transferrin antibody is a 小鼠 单克隆 antibody detecting Transferrin in WB, ELISA, IF 和 Func. Suitable for 人, 大鼠, Pig 和 兔.
产品编号 ABIN2476916
发货至: 中国

Quick Overview for Transferrin 抗体 (N-Term) (ABIN2476916)

抗原

See all Transferrin (TF) 抗体
Transferrin (TF)

适用

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人, 大鼠, Pig, 兔

宿主

  • 177
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  • 14
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  • 1
小鼠

克隆类型

  • 212
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  • 1
单克隆

标记

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This Transferrin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Functional Studies (Func)

克隆位点

HTF-14
  • 抗原表位

    • 12
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    N-Term

    特异性

    Anti transferrin clone HTF-14 is specific for the N-terminal domain of human transferrin and has been shown to block binding of transferrin to the transferrin receptor (CD71). Clone HTF-14 is not able to recognise receptor bound transferrin. Clone HTF-14 recognises a conformational epitope in a loop of the N lobe of transferrin involving the critical Lys-144 residue, also essential for binding of the N lobe to the transferrin receptor (Mason et al.2009)Transferrin is a 77 kDa plasma protein synthesized by the liver involved with the transport of iron. Each transferrin molecule has two domains, both with facility to carry 2 ferric ions. The iron/transferrin complex is essential for haemoglobin synthesis and certain types of cell division.

    交叉反应

    猪, 兔, 大鼠

    产品特性

    Purified IgG

    纯化方法

    Purified

    免疫原

    Purified porcine transferrin

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL
  • 抗原

    Transferrin (TF)

    别名

    TRANSFERRIN

    基因ID

    7018

    UniProt

    P02787

    途径

    Transition Metal Ion Homeostasis
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