Transferrin 抗体 (N-Term)
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北京 101111
Quick Overview for Transferrin 抗体 (N-Term) (ABIN2476916)
抗原
See all Transferrin (TF) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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特异性
- Anti transferrin clone HTF-14 is specific for the N-terminal domain of human transferrin and has been shown to block binding of transferrin to the transferrin receptor (CD71). Clone HTF-14 is not able to recognise receptor bound transferrin. Clone HTF-14 recognises a conformational epitope in a loop of the N lobe of transferrin involving the critical Lys-144 residue, also essential for binding of the N lobe to the transferrin receptor (Mason et al.2009)Transferrin is a 77 kDa plasma protein synthesized by the liver involved with the transport of iron. Each transferrin molecule has two domains, both with facility to carry 2 ferric ions. The iron/transferrin complex is essential for haemoglobin synthesis and certain types of cell division.
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交叉反应
- 猪, 兔, 大鼠
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产品特性
- Purified IgG
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纯化方法
- Purified
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免疫原
- Purified porcine transferrin
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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- Transferrin (TF)
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别名
- TRANSFERRIN
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基因ID
- 7018
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UniProt
- P02787
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途径
- Transition Metal Ion Homeostasis
抗原
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