-
- 抗原 See all Podoplanin (PDPN) 抗体
- Podoplanin (PDPN)
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This Podoplanin antibody is un-conjugated
-
应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This antibody recognizes Human Podoplanin (gp36), a 36 kDa type I cell membrane-associated glycoprotein, with a broad spectrum of distribution, being strongly expressed on the lymphatic endothelium found in lung, placenta and skeletal muscle and to a lesser extent in brain, kidney and liver. Podoplanin is absent on blood endothelium and therefore This antibody is readily able to distinguish between lymphatic vessels and blood vasculature. Although the specific function of this protein is undetermined, Podoplanin is reported to be a reliable indicator of tumour lymphangiogenesis.
- 产品特性
- Purified IgG
- 纯化方法
- Purified
- 免疫原
- ORF Human podoplanin ectodomain expressed in E.coli
- 克隆位点
- 4D5aE5E6
- 亚型
- IgG1
- Top Product
- Discover our top product PDPN Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
-
-
Lymphotoxin beta receptor signaling is required for inflammatory lymphangiogenesis in the thyroid." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 12, pp. 5026-31, (2007) (PubMed).
: "Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survival." in: The American journal of pathology, Vol. 162, Issue 6, pp. 1951-60, (2003) (PubMed).
: "Lymphatic microvessels in the rat remnant kidney model of renal fibrosis: aminopeptidase p and podoplanin are discriminatory markers for endothelial cells of blood and lymphatic vessels." in: Journal of the American Society of Nephrology : JASN, Vol. 14, Issue 8, pp. 1981-9, (2003) (PubMed).
: "
-
Lymphotoxin beta receptor signaling is required for inflammatory lymphangiogenesis in the thyroid." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 12, pp. 5026-31, (2007) (PubMed).
-
- 抗原
- Podoplanin (PDPN)
- 别名
- PODOPLANIN (PDPN 产品)
- 背景
- Synonyms: AGGRUS
- 基因ID
- 10630
- UniProt
- Q86YL7
- 途径
- Dicarboxylic Acid Transport
-