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Podoplanin 抗体

This anti-Podoplanin antibody is a 小鼠 单克隆 antibody detecting Podoplanin in IHC (p) 和 IHC (fro). Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN2476175
发货至: 中国

Quick Overview for Podoplanin 抗体 (ABIN2476175)

抗原

See all Podoplanin (PDPN) 抗体
Podoplanin (PDPN)

适用

  • 92
  • 29
  • 10
  • 3
  • 1
  • 1
  • 1

宿主

  • 67
  • 36
  • 6
  • 5
  • 2
  • 2
  • 2
小鼠

克隆类型

  • 64
  • 55
  • 1
单克隆

标记

  • 79
  • 11
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Podoplanin antibody is un-conjugated

应用范围

  • 92
  • 54
  • 36
  • 31
  • 30
  • 24
  • 15
  • 15
  • 8
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

4D5aE5E6
  • 特异性

    This antibody recognizes Human Podoplanin (gp36), a 36 kDa type I cell membrane-associated glycoprotein, with a broad spectrum of distribution, being strongly expressed on the lymphatic endothelium found in lung, placenta and skeletal muscle and to a lesser extent in brain, kidney and liver. Podoplanin is absent on blood endothelium and therefore This antibody is readily able to distinguish between lymphatic vessels and blood vasculature. Although the specific function of this protein is undetermined, Podoplanin is reported to be a reliable indicator of tumour lymphangiogenesis.

    产品特性

    Purified IgG

    纯化方法

    Purified

    免疫原

    ORF Human podoplanin ectodomain expressed in E.coli

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL
  • Furtado, Marinkovic, Martin, Garin, Hoch, Hubner, Chen, Genden, Skobe, Lira: "Lymphotoxin beta receptor signaling is required for inflammatory lymphangiogenesis in the thyroid." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 12, pp. 5026-31, (2007) (PubMed).

    Dadras, Paul, Bertoncini, Brown, Muzikansky, Jackson, Ellwanger, Garbe, Mihm, Detmar: "Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survival." in: The American journal of pathology, Vol. 162, Issue 6, pp. 1951-60, (2003) (PubMed).

    Matsui, Nagy-Bojarsky, Laakkonen, Krieger, Mechtler, Uchida, Geleff, Kang, Johnson, Kerjaschki, Kang: "Lymphatic microvessels in the rat remnant kidney model of renal fibrosis: aminopeptidase p and podoplanin are discriminatory markers for endothelial cells of blood and lymphatic vessels." in: Journal of the American Society of Nephrology : JASN, Vol. 14, Issue 8, pp. 1981-9, (2003) (PubMed).

  • 抗原

    Podoplanin (PDPN)

    别名

    PODOPLANIN

    背景

    Synonyms: AGGRUS

    基因ID

    10630

    UniProt

    Q86YL7

    途径

    Dicarboxylic Acid Transport
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