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Podoplanin 抗体

PDPN 适用: 人 IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 4D5aE5E6 unconjugated
产品编号 ABIN2476175
发货至: 中国
  • 抗原 See all Podoplanin (PDPN) 抗体
    Podoplanin (PDPN)
    适用
    • 83
    • 25
    • 6
    • 3
    • 1
    宿主
    • 56
    • 31
    • 6
    • 5
    • 2
    • 2
    • 2
    小鼠
    克隆类型
    • 55
    • 48
    • 1
    单克隆
    标记
    • 65
    • 11
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Podoplanin antibody is un-conjugated
    应用范围
    • 79
    • 41
    • 31
    • 27
    • 22
    • 19
    • 15
    • 8
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognizes Human Podoplanin (gp36), a 36 kDa type I cell membrane-associated glycoprotein, with a broad spectrum of distribution, being strongly expressed on the lymphatic endothelium found in lung, placenta and skeletal muscle and to a lesser extent in brain, kidney and liver. Podoplanin is absent on blood endothelium and therefore This antibody is readily able to distinguish between lymphatic vessels and blood vasculature. Although the specific function of this protein is undetermined, Podoplanin is reported to be a reliable indicator of tumour lymphangiogenesis.
    产品特性
    Purified IgG
    纯化方法
    Purified
    免疫原
    ORF Human podoplanin ectodomain expressed in E.coli
    克隆位点
    4D5aE5E6
    亚型
    IgG1
    Top Product
    Discover our top product PDPN Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
  • Furtado, Marinkovic, Martin, Garin, Hoch, Hubner, Chen, Genden, Skobe, Lira: "Lymphotoxin beta receptor signaling is required for inflammatory lymphangiogenesis in the thyroid." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 12, pp. 5026-31, (2007) (PubMed).

    Dadras, Paul, Bertoncini, Brown, Muzikansky, Jackson, Ellwanger, Garbe, Mihm, Detmar: "Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survival." in: The American journal of pathology, Vol. 162, Issue 6, pp. 1951-60, (2003) (PubMed).

    Matsui, Nagy-Bojarsky, Laakkonen, Krieger, Mechtler, Uchida, Geleff, Kang, Johnson, Kerjaschki, Kang: "Lymphatic microvessels in the rat remnant kidney model of renal fibrosis: aminopeptidase p and podoplanin are discriminatory markers for endothelial cells of blood and lymphatic vessels." in: Journal of the American Society of Nephrology : JASN, Vol. 14, Issue 8, pp. 1981-9, (2003) (PubMed).

  • 抗原
    Podoplanin (PDPN)
    别名
    PODOPLANIN (PDPN 产品)
    背景
    Synonyms: AGGRUS
    基因ID
    10630
    UniProt
    Q86YL7
    途径
    Dicarboxylic Acid Transport
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