IFNA 抗体
(3 references)Quick Overview for IFNA 抗体 (ABIN2474115)
抗原
See all IFNA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes chicken Interferon alpha (chIFN-alpha). The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent. This antibody does not cross react with IFN beta or IFN gamma and does not neutralize chIFN-alpha.
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产品特性
- Purified IgG
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纯化方法
- Purified
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免疫原
- Recombinant chicken Interferon alpha.
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亚型
- IgG1
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anti-Interferon alpha (IFNA) (AA 28-227) antibody
IFNA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) antibodyIFNA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-192) antibodyIFNA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-189) antibodyIFNA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 1-187) antibodyIFNA 适用: 豚鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-181) antibodyIFNA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) antibodyIFNA 适用: 大鼠 FACS 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 24-181) antibodyIFNA 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Interferon alpha (IFNA) (AA 47-191) antibodyIFNA 适用: 小鸡 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha (IFNA) (AA 23-187) antibodyIFNA 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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: "Differential host gene expression in cells infected with highly pathogenic H5N1 avian influenza viruses." in: Veterinary immunology and immunopathology, Vol. 125, Issue 3-4, pp. 291-302, (2008) (PubMed).
: "Synthesis of IFN-beta by virus-infected chicken embryo cells demonstrated with specific antisera and a new bioassay." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 24, Issue 3, pp. 179-84, (2004) (PubMed).
: "Cytokines of birds: conserved functions--a largely different look." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 21, Issue 12, pp. 993-1010, (2002) (PubMed).
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: "Differential host gene expression in cells infected with highly pathogenic H5N1 avian influenza viruses." in: Veterinary immunology and immunopathology, Vol. 125, Issue 3-4, pp. 291-302, (2008) (PubMed).
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- IFNA (Interferon alpha (IFNA))
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别名
- IFN alpha
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背景
- Synonyms: INTERFERON ALPHA
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基因ID
- 396398
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UniProt
- P42165
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途径
- JAK/STAT Signaling, TLR signaling, Hepatitis C, Inflammasome
抗原
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