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FANCA 抗体 (AA 995-1009)

FANCA 适用: 人, Chimpanzee WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2470330
发货至: 中国
  • 抗原 See all FANCA 抗体
    FANCA (Fanconi Anemia Group A Protein (FANCA))
    抗原表位
    • 15
    • 12
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 995-1009
    适用
    • 58
    • 18
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    人, Chimpanzee
    宿主
    • 70
    • 3
    克隆类型
    • 71
    • 2
    多克隆
    标记
    • 31
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FANCA antibody is un-conjugated
    应用范围
    • 35
    • 28
    • 13
    • 13
    • 9
    • 9
    • 8
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    FANCA antibody was raised against amino acids 995-1009 of FANCA (Human).
    Top Product
    Discover our top product FANCA Primary Antibody
  • 应用备注
    FANCA antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 20 μg/mL.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    As with all antibodies avoid freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store FANCA antibody at 4 °C or -20 °C.
  • 抗原
    FANCA (Fanconi Anemia Group A Protein (FANCA))
    别名
    FANCA (FANCA 产品)
    别名
    FA antibody, FA-H antibody, FA1 antibody, FAA antibody, FACA antibody, FAH antibody, FANCH antibody, AW208693 antibody, Fanconi anemia complementation group A antibody, Fanconi anemia, complementation group A antibody, FANCA antibody, Fanca antibody
    背景
    FANCA (also called Protein FACA or Fanconi anemia group A protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCA may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Variant 1 (isoform a) encodes the longest transcript. Variant 2 (isoform b) contains an alternate exon, which results in an early stop codon, compared to variant 1. Isoform b has a shorter C-terminus when compared to isoform a. Mutations in this gene are the most common cause of Fanconi anemia.
    基因ID
    2175
    UniProt
    O15360
    途径
    DNA Damage Repair
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