CRTC1 抗体 (AA 19-34)
Our Local Distributor
北京 101111
Quick Overview for CRTC1 抗体 (AA 19-34) (ABIN2470217)
抗原
See all CRTC1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 19-34
-
纯化方法
- Immunoaffinity Chromatography
-
免疫原
- CRTC1 antibody was raised against amino acids 19 - 34 of CRTC1 (Human).
-
-
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) (pSer151) antibody
CRTC1 适用: 人, 小鸡 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 人 WB, IP, ICC, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1B5 unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) (AA 1-248) antibodyCRTC1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) (AA 553-634) antibodyCRTC1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 8F9 unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 人, 小鼠 WB, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) (AA 1-200) antibodyCRTC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB1850 unconjugated Recombinant Antibody
-
-
应用备注
- CRTC1 antibody can be used in ELISA starting at 1:14000 - 1:80000, Western Blot starting at 1:100 - 1:8000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- As with all antibodies avoid freeze/thaw cycles.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store CRTC1 antibody at 4 °C or -20 °C.
-
-
- CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
-
别名
- CRTC1
-
背景
- MECT1 (also known as MucoEpidermoid Carcinoma Translocated 1, Transducer of regulated cAMP response element-binding protein 1, TORC1, and Transducer of CREB protein 1) is a nuclear protein that functions as a transcriptional coactivator for CREB1, which activates transcription through both consensus and variant cAMP response element (CRE) sites. MECT1does not appear to modulate CREB1 DNA-binding activity but enhances the interaction of CREB1 with TAF4/TAFII-130. MECT1 translocates with MAML2 (MasterMind-Like Protein 2) to yield a fusion oncogene: t(11,19) (q21,p13). This translocation occurs in mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas. The novel fusion product that results disrupts the Notch signaling pathway. The fusion protein consists of the N-terminus of MECT1 joined to the C-terminus of MAML2. The reciprocal fusion protein consisting of the N-terminus of MAML2 joined to the C-terminus of MECT1 has been detected in a small number of mucoepidermoid carcinomas. Multiple isoforms have been reported for the MECT1 protein.
-
基因ID
- 23373
-
UniProt
- Q6UUV9
抗原
-
