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BAFF 抗体

TNFSF13B 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal T7-241 unconjugated
产品编号 ABIN2470022
发货至: 中国
  • 抗原 See all BAFF (TNFSF13B) 抗体
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    适用
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    宿主
    • 79
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    小鼠
    克隆类型
    • 90
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    单克隆
    标记
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    This BAFF antibody is un-conjugated
    应用范围
    • 78
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    ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    纯化方法
    Affinity Chromatography
    免疫原
    TNFSF13B monoclonal antibody was raised against recombinant full length TNFSF13B (Human).
    克隆位点
    T7-241
    亚型
    IgG1
    Top Product
    Discover our top product TNFSF13B Primary Antibody
  • 应用备注
    TNFSF13B antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Phosphate-buffered solution, pH 7.2, 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store TNFSF13B antibody at 4 °C. Do not freeze.
  • 抗原
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    别名
    TNFSF13B (TNFSF13B 产品)
    背景
    Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL-1 (for TNF- and ApoL-related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NF-κ,B and c-jun N-terminal Kinase). BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF and its receptors are essential for B cell development, survival, and humoral immune responses. BAFF is involved in the development of autoimmune diseases including systemic lupus erythaematosus and rheumatoid arthritis.
    基因ID
    10673
    UniProt
    Q9Y275
    途径
    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
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