USP18 抗体 (AA 40-49)
Our Local Distributor
北京 101111
Quick Overview for USP18 抗体 (AA 40-49) (ABIN2469597)
抗原
See all USP18 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 40-49
-
纯化方法
- Immunoaffinity Chromatography
-
免疫原
- USP18 antibody was raised against amino acids 40 - 49 of USP18 (Human).
-
-
-
-
应用备注
- USP18 antibody can be used in ELISA starting at 1:10000 - 1:50000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- As with all antibodies avoid freeze/thaw cycles.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store USP18 antibody at 4 °C or -20 °C.
-
-
- USP18 (Ubiquitin Specific Peptidase 18 (USP18))
-
别名
- USP18
-
背景
- UBP43 (also known as ISG43, Ubl thiolesterase 18, ISG15-specific processing protease, 43 kDa ISG15-specific protease, ubiquitin specific protease 18 or USP18) is a member of the deubiquitinating protease family of enzymes, which removes ubiquitin adducts from a broad range of protein substrates. Deletion of the UBP43 gene in mouse leads to a massive increase of ISG15 conjugates in tissues indicating that UBP43 is a major ISG15-specific protease. UBP43 is the first ISG15-specific protease reported. Both ISG15 and UBP43 genes are known to be strongly induced by interferon, genotoxic stress, and viral infection. Thus UBP43 may be necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms.
-
基因ID
- 11274
-
UniProt
- Q9UMW8
抗原
-