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TYRO3 抗体 (truncated)

This anti-TYRO3 antibody is a 小鼠 单克隆 antibody detecting TYRO3 in WB, ELISA 和 IF. Suitable for 人.
产品编号 ABIN2464119
发货至: 中国

Quick Overview for TYRO3 抗体 (truncated) (ABIN2464119)

抗原

See all TYRO3 抗体
TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

适用

  • 48
  • 13
  • 7
  • 4

宿主

  • 30
  • 22
  • 3
  • 1
小鼠

克隆类型

  • 27
  • 24
  • 2
  • 1
单克隆

标记

  • 45
  • 3
  • 3
  • 1
  • 1
  • 1
This TYRO3 antibody is un-conjugated

应用范围

  • 36
  • 24
  • 17
  • 9
  • 9
  • 8
  • 8
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)

克隆位点

1C10E8-9A3F2
  • 抗原表位

    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    truncated

    免疫原

    Ni-NTA purified truncated recombinant TYRO3 expressed in E. Coli strain BL21 (DE3).

    亚型

    IgG1
  • 应用备注

    Western Blot:1:500 - 1:2,000
    IF:1:50 - 1:200
    ELISA:Propose dilution 1:10,000.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

    储存条件

    -20 °C

    储存方法

    TYRO3 monoclonal antibody can be stored at -20 °C, stable for one year.
  • 抗原

    TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

    别名

    TYRO3

    背景

    Tyrosine-protein kinase (TYRO3) belongs to the Tyr protein kinase family (AXL/UFO subfamily). The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse(also referred to as Tyro3 or Sky) and UFO (also called Tyro7 or Axl). Two distinct isoforms of Rse, designated Brt and Etk-2, have been described. Brt differs from Rse at its C-terminus, but more importantly lacks the N-terminal 31 amino acid signal peptide sequence present in Rse, which is replaced by a 27 amino acid Brt-specific sequence. It has been suggested that as a result of this alternative splicing event, Brt resides in the cytoplasm, unlike Rse which is expressed on the cell surface. Ekt-2 also lacks an N-terminal signal peptide which is substituted with a 45 amino acid Ekt-2-specific sequence. Protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.

    基因ID

    7301

    UniProt

    Q06418

    途径

    RTK signaling
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