TYRO3 抗体 (truncated)
Our Local Distributor
北京 101111
Quick Overview for TYRO3 抗体 (truncated) (ABIN2464119)
抗原
See all TYRO3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- truncated
-
免疫原
- Ni-NTA purified truncated recombinant TYRO3 expressed in E. Coli strain BL21 (DE3).
-
亚型
- IgG1
-
-
-
-
应用备注
-
Western Blot:1:500 - 1:2,000
IF:1:50 - 1:200
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
-
-
-
缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
储存条件
- -20 °C
-
储存方法
- TYRO3 monoclonal antibody can be stored at -20 °C, stable for one year.
-
-
- TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
-
别名
- TYRO3
-
背景
- Tyrosine-protein kinase (TYRO3) belongs to the Tyr protein kinase family (AXL/UFO subfamily). The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse(also referred to as Tyro3 or Sky) and UFO (also called Tyro7 or Axl). Two distinct isoforms of Rse, designated Brt and Etk-2, have been described. Brt differs from Rse at its C-terminus, but more importantly lacks the N-terminal 31 amino acid signal peptide sequence present in Rse, which is replaced by a 27 amino acid Brt-specific sequence. It has been suggested that as a result of this alternative splicing event, Brt resides in the cytoplasm, unlike Rse which is expressed on the cell surface. Ekt-2 also lacks an N-terminal signal peptide which is substituted with a 45 amino acid Ekt-2-specific sequence. Protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.
-
基因ID
- 7301
-
UniProt
- Q06418
-
途径
- RTK signaling
抗原
-