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TYK2 抗体 (truncated)

This anti-TYK2 antibody is a 小鼠 单克隆 antibody detecting TYK2 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN2464118
发货至: 中国

Quick Overview for TYK2 抗体 (truncated) (ABIN2464118)

抗原

See all TYK2 抗体
TYK2 (Tyrosine Kinase 2 (TYK2))

适用

  • 86
  • 36
  • 27
  • 4
  • 1
  • 1
  • 1

宿主

  • 77
  • 11
小鼠

克隆类型

  • 77
  • 12
单克隆

标记

  • 45
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TYK2 antibody is un-conjugated

应用范围

  • 69
  • 34
  • 21
  • 13
  • 13
  • 13
  • 12
  • 11
  • 8
  • 5
  • 2
  • 1
Western Blotting (WB), ELISA

克隆位点

8G8E9-8G9H5
  • 抗原表位

    • 17
    • 15
    • 15
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    truncated

    免疫原

    Ni-NTA purified truncated recombinant Tyk2 expressed in E. Coli strain BL21 (DE3).

    亚型

    IgG1
  • 应用备注

    Western Blot:1:500 - 1:2,000

    ELISA:Propose dilution 1:10,000.

    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

    储存条件

    -20 °C

    储存方法

    Tyk2 monoclonal antibody can be stored at -20 °C, stable for one year.
  • 抗原

    TYK2 (Tyrosine Kinase 2 (TYK2))

    别名

    Tyk2

    背景

    Tyk2 (tyrosine kinase 2),with 1187-amino acid protein (about 131 kDa), belongs to the family of non-receptor janus tyrosine kinases, which also includes Jak1, Jak2, and Jak3. Kinases of the Jak family regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Tyk2 is activated by a variety of cytokines: IFN-alpha, IFN-beta, IL-6, IL-10, IL-12, and IL-13 and promotes IFN-gamma production by Th1-type CD4 cells. Tyk2 can be viewed as a dual-function Jak, mediating both pro-inflammatory and anti-inflammatory cytokine responses. Tyk2 is also an important regulator of lymphoid tumor surveillance.

    基因ID

    7297

    UniProt

    P29597

    途径

    JAK/STAT Signaling, Hepatitis C
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