TYK2 抗体 (truncated)
Our Local Distributor
北京 101111
Quick Overview for TYK2 抗体 (truncated) (ABIN2464118)
抗原
See all TYK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- truncated
-
免疫原
- Ni-NTA purified truncated recombinant Tyk2 expressed in E. Coli strain BL21 (DE3).
-
亚型
- IgG1
-
-
-
-
应用备注
-
Western Blot:1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
储存条件
- -20 °C
-
储存方法
- Tyk2 monoclonal antibody can be stored at -20 °C, stable for one year.
-
-
- TYK2 (Tyrosine Kinase 2 (TYK2))
-
别名
- Tyk2
-
背景
- Tyk2 (tyrosine kinase 2),with 1187-amino acid protein (about 131 kDa), belongs to the family of non-receptor janus tyrosine kinases, which also includes Jak1, Jak2, and Jak3. Kinases of the Jak family regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Tyk2 is activated by a variety of cytokines: IFN-alpha, IFN-beta, IL-6, IL-10, IL-12, and IL-13 and promotes IFN-gamma production by Th1-type CD4 cells. Tyk2 can be viewed as a dual-function Jak, mediating both pro-inflammatory and anti-inflammatory cytokine responses. Tyk2 is also an important regulator of lymphoid tumor surveillance.
-
基因ID
- 7297
-
UniProt
- P29597
-
途径
- JAK/STAT Signaling, Hepatitis C
抗原
-