GSTP1 抗体 (truncated)
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北京 101111
Quick Overview for GSTP1 抗体 (truncated) (ABIN2464062)
抗原
See all GSTP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- truncated
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免疫原
- Ni-NTA purified truncated recombinant GSTP1 expressed in E. Coli strain BL21 (DE3).
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亚型
- IgG1
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应用备注
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Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- -20 °C
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储存方法
- GSTP1 monoclonal antibody can be stored at -20 °C, stable for one year.
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- GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))
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别名
- GSTP1
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背景
- GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, which is located on chromosome 11q13 , is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90 % ) of prostate carcinomas and is associated with transcriptional down-regulation.
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基因ID
- 2950
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UniProt
- P09211
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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