ELK1 抗体 (truncated)
Quick Overview for ELK1 抗体 (truncated) (ABIN2464047)
抗原
See all ELK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- truncated
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免疫原
- Ni-NTA purified truncated recombinant ELK1 expressed in E. Coli strain BL21 (DE3).
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亚型
- IgG1
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anti-ELK1, Member of ETS Oncogene Family (ELK1) (pSer389) antibody
ELK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (pSer383) antibodyELK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (C-Term) antibodyELK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) antibodyELK1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 3H6D12 unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (pSer383) antibodyELK1 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (AA 247-403) antibodyELK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (AA 67-166) antibodyELK1 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 2G6 unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (C-Term) antibodyELK1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (pSer383) antibodyELK1 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-ELK1, Member of ETS Oncogene Family (ELK1) (AA 90-250) antibodyELK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot:1:500 - 1:1,000
IHC(P):1:500 - 1:1,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- -20 °C
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储存方法
- ELK1 monoclonal antibody can be stored at -20 °C, stable for one year.
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- ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))
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别名
- ELK1
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背景
- The transcription factor ELK1 is a family of member of ETS oncogene family and of the ternary complex factor (TCF) subfamily,which is located on chromosome Xp11.2 and stimulates transcription. binds to purine-rich DNA sequences. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Elk1 is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C terminus,It appears to be a direct target of activated MAP kinase. Biochemical studies indicate that Elk1 is a good substrate for MAP kinase, the kinetics of Elk1phosphorylation and activation correlate with MAP kinase activity, and interfering mutants of MAP kinase block Elk1 activation in vivo. More recent studies have shown that Elk1 is also a target of the Stress Activated Kinase SAPK/JNK. Phosphorylation of Elk1 has also been implicated in synaptic plasticity in the adult hippocampus.
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基因ID
- 2002
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UniProt
- P19419
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
抗原
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