KIT 抗体 (truncated)
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Quick Overview for KIT 抗体 (truncated) (ABIN2464038)
抗原
See all KIT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- truncated
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纯化方法
- Antibody is purified by protein A affinity chromatography.
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免疫原
- Ni-NTA purified truncated recombinant C-kit expressed in E. Coli strain BL21 (DE3).
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亚型
- IgG1
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应用备注
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Dilution
ELISA:Propose dilution 1:10,000
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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状态
- Liquid
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注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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储存条件
- -20 °C
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储存方法
- C-Kit monoclonal antibody can be stored at -20 °C, stable for one year.
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- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
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别名
- CKit
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背景
- C-kit (CD117,145 kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.
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基因ID
- 3815
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UniProt
- P10721
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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