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BLK 抗体 (truncated)

This anti-BLK antibody is a 小鼠 单克隆 antibody detecting BLK in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN2464018
发货至: 中国

Quick Overview for BLK 抗体 (truncated) (ABIN2464018)

抗原

See all BLK 抗体
BLK (B Lymphoid Tyrosine Kinase (BLK))

适用

  • 66
  • 24
  • 15
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 53
  • 10
  • 1
小鼠

克隆类型

  • 55
  • 11
单克隆

标记

  • 39
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This BLK antibody is un-conjugated

应用范围

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  • 34
  • 28
  • 13
  • 13
  • 7
  • 6
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

9D10B7H6-9D10A8F8
  • 抗原表位

    • 15
    • 9
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    truncated

    免疫原

    Ni-NTA purified truncated recombinant BLK expressed in E. Coli strain BL21 (DE3).

    亚型

    IgG1
  • 应用备注

    Western Blot:1:500 - 1:2,000
    IHC(P):1:500 - 1:2,000
    IHC(F):1:500 - 1:2,000
    ELISA:Propose dilution 1:10,000.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

    储存条件

    -20 °C

    储存方法

    BLK monoclonal antibody can be stored at -20 °C, stable for one year.
  • 抗原

    BLK (B Lymphoid Tyrosine Kinase (BLK))

    别名

    BLK

    背景

    BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56 kDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.

    基因ID

    640

    UniProt

    P51451

    途径

    Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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