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LMAN1 抗体

The 兔 多克隆 anti-LMAN1 antibody is suitable to detect LMAN1 in samples from 人, 小鼠, 大鼠 和 犬. It has been validated for WB 和 ELISA.
产品编号 ABIN2462990
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for LMAN1 抗体 (ABIN2462990)

抗原

See all LMAN1 抗体
LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

适用

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  • 1
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人, 小鼠, 大鼠, 犬

宿主

  • 69
  • 2

克隆类型

  • 36
  • 35
多克隆

标记

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  • 5
  • 3
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  • 3
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  • 3
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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This LMAN1 antibody is un-conjugated

应用范围

  • 65
  • 39
  • 28
  • 25
  • 14
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  • 13
  • 5
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  • 3
  • 1
  • 1
Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by protein A chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LMAN1.
  • 应用备注

    LMAN1 antibody can be used for detection of LMAN1 by ELISA at 1:1562500. LMAN1 antibody can be used for detection of LMAN1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store LMAN1 antibody at -20 °C.
  • 抗原

    LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

    别名

    LMAN1

    背景

    LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in its gene are associated with a coagulation defect. Using positional cloning, its gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

    分子量

    54 kDa

    基因ID

    3998

    NCBI登录号

    NP_005561

    UniProt

    P49257
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