LMAN1 抗体 (N-Term)
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北京 101111
Quick Overview for LMAN1 抗体 (N-Term) (ABIN2782680)
抗原
See all LMAN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- LMAN1 Antibody - N-terminal region
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序列
- DPAVALPHRR FEYKYSFKGP HLVQSDGTVP FWAHAGNAIP SSDQIRVAPS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against LMAN1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human LMAN1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46613-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))
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别名
- LMAN1
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背景
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Background Information: LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in its gene are associated with a coagulation defect. Using positional cloning, its gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Name: Lectin, mannose-binding, 1
Alternative Symbols: MR60, gp58, F5F8D, FMFD1, MCFD1, ERGIC53, ERGIC-53
Protein Name: Protein ERGIC-53
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分子量
- 54kDa
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基因ID
- 3998
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NCBI登录号
- NP_005561
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UniProt
- P49257
抗原
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