RRM1 抗体
Quick Overview for RRM1 抗体 (ABIN2462920)
抗原
See all RRM1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by protein A chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RRM1.
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anti-Ribonucleotide Reductase M1 (RRM1) (AA 593-792) antibody
RRM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 541-792) antibodyRRM1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2D6D8 unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 1-213) antibodyRRM1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (Center) antibodyRRM1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 593-792) antibodyRRM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 541-792) antibodyRRM1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5G5 unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 733-778) antibodyRRM1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) antibodyRRM1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (Internal Region) antibodyRRM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) antibodyRRM1 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 3D6H5 unconjugated
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应用备注
- RRM1 antibody can be used for detection of RRM1 by ELISA at 1:62500. RRM1 antibody can be used for detection of RRM1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store RRM1 antibody at -20 °C.
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- RRM1 (Ribonucleotide Reductase M1 (RRM1))
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别名
- RRM1
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背景
- RRM1 is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. Its gene is located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. Its gene may play a role in malignancies and disease that involve this region.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes one of two non-identical subunits which constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. This gene is oriented in a head-to-tail configuration with the stromal interaction molecule 1 gene (STIM1), with the 3' end of STIM1 situated 1.6 kb from the 5' end of this gene.
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分子量
- 90 kDa
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基因ID
- 6240
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NCBI登录号
- NP_001024
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UniProt
- P23921
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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