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IRF6 抗体

This anti-IRF6 antibody is a 兔 多克隆 antibody detecting IRF6 in WB 和 ELISA. Suitable for 人, 小鼠, 大鼠, 犬 和 斑马鱼.
产品编号 ABIN2462721
发货至: 中国

Quick Overview for IRF6 抗体 (ABIN2462721)

抗原

See all IRF6 抗体
IRF6 (Interferon Regulatory Factor 6 (IRF6))

适用

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人, 小鼠, 大鼠, 犬, 斑马鱼

宿主

  • 67
  • 8
  • 1

克隆类型

  • 61
  • 15
多克隆

标记

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  • 3
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  • 2
  • 1
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This IRF6 antibody is un-conjugated

应用范围

  • 51
  • 16
  • 13
  • 9
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  • 8
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  • 1
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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by protein A chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IRF6.
  • 应用备注

    IRF6 antibody can be used for detection of IRF6 by ELISA at 1:312500. IRF6 antibody can be used for detection of IRF6 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store IRF6 antibody at -20 °C.
  • 抗原

    IRF6 (Interferon Regulatory Factor 6 (IRF6))

    别名

    IRF6

    背景

    IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

    分子量

    65 kDa, 69 kDa

    基因ID

    3664

    NCBI登录号

    NP_006138

    UniProt

    O14896
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