PRP19 抗体
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北京 101111
Quick Overview for PRP19 抗体 (ABIN2462670)
抗原
See all PRP19 (PRPF19) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by protein A chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PRPF19.
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anti-Pre-mRNA Processing Factor 19 (PRPF19) (AA 127-416) antibody
PRPF19 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) (AA 1-90) antibodyPRPF19 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) (AA 1-90) antibodyPRPF19 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) antibodyPRPF19 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) (AA 4-33), (N-Term) antibodyPRPF19 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20845 unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) (Middle Region) antibodyPRPF19 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) (N-Term) antibodyPRPF19 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) (AA 151-200) antibodyPRPF19 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, Pig, 豚鼠, Bat, 猴, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) antibodyPRPF19 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) (Internal Region) antibodyPRPF19 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- PRPF19 antibody can be used for detection of PRPF19 by ELISA at 1:312500. PRPF19 antibody can be used for detection of PRPF19 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PRPF19 antibody at -20 °C.
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- PRP19 (PRPF19) (Pre-mRNA Processing Factor 19 (PRPF19))
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别名
- PRPF19
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背景
- PRPF19 plays a role in DNA double-strand break (DSB) repair and pre-mRNA splicing reaction. It binds double-stranded DNA in a sequence-nonspecific manner. PRPF19 acts as a structural component of the nuclear framework. It may also serve as a support for spliceosome binding and activity. It is essential for spliceosome assembly in a oligomerization-dependent manner and might also be important for spliceosome stability. It also may have E3 ubiquitin ligase activity. The PSO4 complex is required in the DNA interstrand cross-links (ICLs) repair process. Overexpression of PRPF19 might extend the cellular life span by increasing the resistance to stress or by improving the DNA repair capacity of the cells.In S. cerevisiae, Pso4 has pleiotropic functions in DNA recombination and in error-prone nonhomologous end-joining DNA repair.
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分子量
- 55 kDa
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基因ID
- 27339
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NCBI登录号
- NP_055317
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UniProt
- Q9UMS4
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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