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Tropomyosin 抗体

TPM1 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2462395
发货至: 中国
  • 抗原 See all Tropomyosin (TPM1) 抗体
    Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
    适用
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    • 5
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    人, 大鼠, 小鼠, 斑马鱼, 犬
    宿主
    • 40
    • 11
    克隆类型
    • 31
    • 20
    多克隆
    标记
    • 27
    • 4
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    This Tropomyosin antibody is un-conjugated
    应用范围
    • 25
    • 16
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Antibody is purified by protein A chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TPM1.
    Top Product
    Discover our top product TPM1 Primary Antibody
  • 应用备注
    TPM1 antibody can be used for detection of TPM1 by ELISA at 1:312500. TPM1 antibody can be used for detection of TPM1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store TPM1 antibody at -20 °C.
  • 抗原
    Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
    别名
    TPM1 (TPM1 产品)
    别名
    alpha-fTM antibody, Tm7 antibody, tpm1 antibody, MGC84844 antibody, AA986836 antibody, AI854628 antibody, TM2 antibody, Tm3 antibody, Tmpa antibody, Tpm-1 antibody, alpha-TM antibody, Alpha-tm antibody, Tma2 antibody, Tmsa antibody, TPM1 antibody, fb37a09 antibody, tm antibody, wu:fb37a09 antibody, CH1 antibody, alpha-tm antibody, alpha-tropomyosin antibody, C15orf13 antibody, CMD1Y antibody, CMH3 antibody, HTM-alpha antibody, TMSA antibody, TPMA antibody, Tm1 antibody, zgc:171719 antibody, zgc:55951 antibody, zgc:77009 antibody, tropomyosin 1 (alpha) antibody, tropomyosin antibody, tropomyosin 1 antibody, tropomyosin 1, alpha antibody, alpha-tropomyosin antibody, tropomyosin 1 L homeolog antibody, TPM1 antibody, tm7 antibody, Tpm1 antibody, tpma antibody, tpm1.L antibody, Smp_044010.2 antibody, LOC732984 antibody, tpm1 antibody
    背景
    TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
    分子量
    31 kDa, 33 kDa, 33 kDa, 33 kDa
    基因ID
    7168
    NCBI登录号
    NP_000357
    UniProt
    P09493
    途径
    Regulation of Actin Filament Polymerization
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