Tropomyosin 抗体
Quick Overview for Tropomyosin 抗体 (ABIN2462395)
抗原
See all Tropomyosin (TPM1) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by protein A chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TPM1.
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anti-Tropomyosin 1 (Alpha) (TPM1) (AA 1-245) antibody
TPM1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) (N-Term) antibodyTPM1 适用: 人, 大鼠, 小鼠, 斑马鱼, 兔, Cow, 犬, 马, 豚鼠, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) (N-Term) antibodyTPM1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) (AA 101-150) antibodyTPM1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) (N-Term) antibodyTPM1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) (N-Term) antibodyTPM1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- TPM1 antibody can be used for detection of TPM1 by ELISA at 1:312500. TPM1 antibody can be used for detection of TPM1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store TPM1 antibody at -20 °C.
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- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
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别名
- TPM1
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背景
- TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
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分子量
- 31 kDa, 33 kDa, 33 kDa, 33 kDa
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基因ID
- 7168
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NCBI登录号
- NP_000357
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UniProt
- P09493
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途径
- Regulation of Actin Filament Polymerization
抗原
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