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NONO 抗体

NONO 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2462238
发货至: 中国
  • 抗原 See all NONO 抗体
    NONO (Non-POU Domain Containing, Octamer-Binding (NONO))
    适用
    • 75
    • 35
    • 31
    • 15
    • 9
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 69
    • 5
    • 2
    克隆类型
    • 61
    • 15
    多克隆
    标记
    • 36
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NONO antibody is un-conjugated
    应用范围
    • 58
    • 35
    • 26
    • 17
    • 14
    • 14
    • 14
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by protein A chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NONO.
    Top Product
    Discover our top product NONO Primary Antibody
  • 应用备注
    NONO antibody can be used for detection of NONO by ELISA at 1:312500. NONO antibody can be used for detection of NONO by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store NONO antibody at -20 °C.
  • 抗原
    NONO (Non-POU Domain Containing, Octamer-Binding (NONO))
    别名
    NONO (NONO 产品)
    别名
    NMT55 antibody, NRB54 antibody, P54 antibody, P54NRB antibody, nmt55 antibody, nrb54 antibody, p54nrb antibody, xp54nrb antibody, AA407051 antibody, AV149256 antibody, nonA antibody, non-POU domain containing octamer binding antibody, non-POU domain containing, octamer-binding antibody, non-POU domain containing, octamer binding L homeolog antibody, non-POU-domain-containing, octamer binding protein antibody, NONO antibody, Nono antibody, nono.L antibody
    背景
    NONO is DNA- and RNA binding protein, involved in several nuclear processes. It binds the conventional octamer sequence in double stranded DNA. It also binds single-stranded DNA and RNA at a site independent of the duplex site. It is involved in pre-mRNA splicing and interacts with U5 snRNA. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs, be involved in DNA unwinding by modulating the function of topoisomerase I/TOP1 and be involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V (D)J recombination and may stabilize paired DNA ends. NONO binds to an enhancer element in long terminal repeats of endogenous intracisternal A particles (IAPs) and activates transcription.
    分子量
    52 kDa
    基因ID
    4841
    NCBI登录号
    NP_031389
    UniProt
    Q15233
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