Fibrillarin 抗体
Quick Overview for Fibrillarin 抗体 (ABIN2462108)
抗原
See all Fibrillarin (FBL) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by protein A chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FBL.
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anti-Fibrillarin (FBL) antibody
FBL 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibrillarin (FBL) (AA 100-321) antibodyFBL 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibrillarin (FBL) antibodyFBL 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Fibrillarin (FBL) antibodyFBL 适用: 人 WB, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibrillarin (FBL) antibodyFBL 适用: Saccharomyces cerevisiae WB, IF 宿主: 小鼠 Monoclonal 38F3 unconjugated
anti-Fibrillarin (FBL) (AA 1-321) antibodyFBL 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G9-E4 unconjugated
anti-Fibrillarin (FBL) (N-Term) antibodyFBL 适用: 人, 大鼠, 小鼠, 犬, Cow, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibrillarin (FBL) (Internal Region) antibodyFBL 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibrillarin (FBL) (AA 61-110) antibodyFBL 适用: 人, 大鼠, 小鼠, 犬, Cow, 猴, 豚鼠, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fibrillarin (FBL) (N-Term) antibodyFBL 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- FBL antibody can be used for detection of FBL by ELISA at 1:12500. FBL antibody can be used for detection of FBL by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store FBL antibody at -20 °C.
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- Fibrillarin (FBL)
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别名
- FBL
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背景
- FBL is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. FBL contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.
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分子量
- 35 kDa
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基因ID
- 2091
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NCBI登录号
- NP_001427
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UniProt
- P22087
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途径
- Ribonucleoside Biosynthetic Process
抗原
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