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SIAH1 抗体

This anti-SIAH1 antibody is a 兔 多克隆 antibody detecting SIAH1 in WB 和 ELISA. Suitable for 人, 大鼠, 小鼠, 犬 和 斑马鱼.
产品编号 ABIN2461673
发货至: 中国

Quick Overview for SIAH1 抗体 (ABIN2461673)

抗原

See all SIAH1 抗体
SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))

适用

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人, 大鼠, 小鼠, 犬, 斑马鱼

宿主

  • 51
  • 2
  • 2

克隆类型

  • 53
  • 2
多克隆

标记

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This SIAH1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by protein A chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SIAH1.
  • 应用备注

    SIAH1 antibody can be used for detection of SIAH1 by ELISA at 1:312500. SIAH1 antibody can be used for detection of SIAH1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store SIAH1 antibody at -20 °C.
  • 抗原

    SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))

    别名

    SIAH1

    背景

    SIAH1 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterizedThis gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

    分子量

    31 kDa

    基因ID

    6477

    NCBI登录号

    NP_003022

    UniProt

    Q8IUQ4
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