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MCM6 抗体

This anti-MCM6 antibody is a 兔 多克隆 antibody detecting MCM6 in IHC, WB 和 ELISA. Suitable for 人 和 犬.
产品编号 ABIN2461393
发货至: 中国

Quick Overview for MCM6 抗体 (ABIN2461393)

抗原

See all MCM6 抗体
MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

适用

  • 60
  • 21
  • 15
  • 9
  • 7
  • 7
  • 7
  • 4
  • 2
  • 1
  • 1
人, 犬

宿主

  • 38
  • 18
  • 4

克隆类型

  • 42
  • 18
多克隆

标记

  • 47
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MCM6 antibody is un-conjugated

应用范围

  • 45
  • 44
  • 17
  • 17
  • 13
  • 11
  • 10
  • 6
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Western Blotting (WB), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MCM6.
  • 应用备注

    MCM6 antibody can be used for detection of MCM6 by ELISA at 1:312500. MCM6 antibody can be used for detection of MCM6 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store MCM6 antibody at -20 °C.
  • 抗原

    MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

    别名

    MCM6

    背景

    The protein encoded by the MCM6 gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

    分子量

    90 kDa

    基因ID

    4175

    NCBI登录号

    NP_005906

    UniProt

    Q14566

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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