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E2F6 抗体

This anti-E2F6 antibody is a 兔 多克隆 antibody detecting E2F6 in WB, IHC 和 ELISA. Suitable for 人, 小鼠, 大鼠 和 犬.
产品编号 ABIN2460397
发货至: 中国

Quick Overview for E2F6 抗体 (ABIN2460397)

抗原

See all E2F6 抗体
E2F6 (E2F Transcription Factor 6 (E2F6))

适用

  • 33
  • 16
  • 11
  • 6
  • 5
  • 5
  • 4
  • 4
  • 3
  • 1
  • 1
人, 小鼠, 大鼠, 犬

宿主

  • 25
  • 7
  • 1

克隆类型

  • 24
  • 9
多克隆

标记

  • 33
This E2F6 antibody is un-conjugated

应用范围

  • 30
  • 11
  • 10
  • 10
  • 5
  • 5
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 纯化方法

    Antibody is purified by peptide affinity chromatography method.

    免疫原

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human E2F6.
  • 应用备注

    E2F6 antibody can be used for detection of E2F6 by ELISA at 1:62500. E2F6 antibody can be used for detection of E2F6 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    浓度

    1 mg/mL

    缓冲液

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    注意事项

    As with any antibody avoid repeat freeze-thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store E2F6 antibody at -20 °C.
  • 抗原

    E2F6 (E2F Transcription Factor 6 (E2F6))

    别名

    E2F6

    背景

    E2F6 encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max.

    分子量

    14 kDa

    基因ID

    1876

    NCBI登录号

    NP_997705

    UniProt

    Q6Q9Z5
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