FGD1 抗体
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北京 101111
Quick Overview for FGD1 抗体 (ABIN2460269)
抗原
See all FGD1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by peptide affinity chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FGD1.
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应用备注
- FGD1 antibody can be used for detection of FGD1 by ELISA at 1:312500. FGD1 antibody can be used for detection of FGD1 by western blot at 2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store FGD1 antibody at -20 °C.
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- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
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别名
- FGD1
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背景
- FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.
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分子量
- 107 kDa
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基因ID
- 2245
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NCBI登录号
- NP_004454
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UniProt
- P98174
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途径
- Neurotrophin Signaling Pathway
抗原
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